Pregabalin and Mecobalamin Capsules




Pregabalin and Mecobalamin Capsules are indicated for treating spinal cord injury-related neuropathic pain, fibromyalgia, fibromyalgia, perioperative pain, chronic pain, and peripheral neuropathy. Additionally, this medicine helps in improving energy, learning, memory, supports nervous and immune systems. Also, it promotes cardiovascular health and is scientifically proven for controlling plasma levels of homocysteine.

Pregabalin and Mecobalamin Capsules promote regeneration of neuronal myelin sheath and are able to reduce the release of neurotransmitters. This effective capsule contains two effective generic drugs: Pregabalin and Mecobalamin. Collectively, they work to help an individual rid of the above condition.

With its analgesic property, Pregabalin reduces neuropathy-related pain symptoms. On the other hand, Mecobalamin acts as a cofactor for methionine synthase to convert methyl groups from homocysteine to methionine. A high homocysteine level is a predominant risk factor for CAD (coronary artery disease). Methionine can be transformed into s-adenosylmethionine, which is used in methylation reactions that help people reduce depression.

All above, pregabalin binds to the voltage-dependent calcium channel. It reduces the release of substance P, calcitonin-related peptides, glutamate, and norepinephrine. The mechanism of action of pregabalin is opposite to other anxiolytics, it neither binds to GABA receptors nor influences GABA metabolism or currents. That’s how Pregabalin and Mecobalamin Capsules works.

Note:  The Cmax of pregabalin can be obtained within one hour of administration and Mecobalamin takes at least 3 hours.

Precautions for Pregabalin and Mecobalamin Capsules

An individual patient should use Pregabalin and Mecobalamin Capsules IP while giving consideration to the official guidelines to ensure proper use. Most importantly, one should avoid driving vehicles and practicing dangerous activities like working on heights, and many. In short, avoid activities that require speed of psychomotor reactions or a high concentration.


  • Individuals who are allergic to vitamin B12 supplements and pregabalin should avoid taking this medicine.
  • Pregabalin and Mecobalamin Capsules fall under the USFDA pregnancy category C. May it is harmful to the unborn baby or not. Consult the healthcare provider before commencing treatment with this medicine. Discuss the risks and benefits associated with the administration.
  • Medics determine the dosage of this medicine considering numerous factors like age, gender, tolerance, etc. So don’t take less or more out of the medication unless the doctor directs.
  • Due to limited studies, it is unknown whether this medicine passes through breast milk or not. To be on the safe side, nursing mothers should avoid breastfeeding while using this medicine.
  • The route of administration of Pregabalin and Mecobalamin Capsules IP is oral. It should be taken by mouth with a full glass of water. With food, the rate of absorption of this medicine can be increased.


There is no evidence of serious side effects of pregabalin mecobalamin on the liver or any other organ of the body. However, some individual complains that it has minimal negative effects. In general, they last until the treatment is not over. They are mild to moderate. To know more deets about the list of side effects, confer with your healthcare provider.

Adverse reactions:-

  • Constipation,
  • Drowsiness,
  • Dry mouth, and dizziness.
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