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Mirtazapine mouth-dissolving tablets are majorly prescribed for the treatment of depression. It belongs to the category of medicines called anti-depressants. Mirtazapine starts to work more quickly than other antidepressants. The medication can also be prescribed in the treatment of obsessive-compulsive disorder (OCD), and anxiety disorders. Depression is a mood disorder associated with symptoms such as prolonged sadness, unhappiness, anger, hopelessness, or loss that interferes with a person’s daily activities. It is advised to store the Mirtazapine in a cool and dry environment away from direct sunlight. 

Follow the dosage and duration prescribed by your healthcare professional. Do not skip doses or indulge in the overdosage. Keep the tablet in your mouth until it fully disintegrates in the mouth. Do not swallow the tablet with a glass of water as it is a mouth-dissolving tablet. Some people may observe a few side effects such as sleepiness, drowsiness, weight gain, dry mouth, headache, nausea, vomiting, and tiredness. Inform your doctor if you are allergic to Mirtazapine or similar medicines. 

Medical Benefits of Mirtazapine Mouth Dissolving Tablets 

Mirtazapine tablets are primarily prescribed for the treatment of major depressive disorders or depression. It belongs to the category of medicines called tetracyclic anti-depressants. The medicine works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance. It is also highly beneficial for the treatment of obsessive-compulsive disorder (OCD) and anxiety disorders. The mouth-dissolving property of the tablets helps in the better absorption of the medicine and is relatively more effective.  

Directions for Use 

Carefully read the description given along the tablets. With dry hands, remove the foil backing of tablets and gently remove the tablet. Place the tablet in the mouth and allow it to dissolve, then swallow. You can also take these tablets with water, however, they also work fine by dissolving in the mouth. 

Side Effects of Mirtazapine Mouth Dissolving Tablets

There are mild to temporary side effects of Mirtazapine Mouth Dissolving Tablets that do not last for a long time. The side effects are individualistic in nature and depend on the health conditions and response to the treatment. Inform your doctor if your side effects get worse or persist with time. The range of side effects noticed on using the Mirtazapine Mouth Dissolving Tablets are mentioned as follows: 

  • Sleepiness
  • Drowsiness
  • Weight gain
  • Dry mouth
  • Headache
  • Nausea
  • Vomiting
  • Tiredness

Drug Interactions 

Mirtazapine Mouth Dissolving Tablets may interact with other medicines and cause adverse side effects. The medications also have a tendency to interact with other medicines and diseases. Avoid taking Mirtazapine Mouth Dissolving Tablets with the following mentioned medications: 

  • Anti-depressants (moclobemide, tranylcypromine, selegiline, nefazodone, duloxetine, sertraline, escitalopram)
  • Antibiotics (erythromycin, linezolid)
  • Anti-fungal (ketoconazole)
  • Anti-TB (rifampicin)
  • Antipsychotic (olanzapine, aripiprazole, quetiapine)
  • Anti-convulsant (carbamazepine, phenytoin, pregabalin)
  • Pain killer (tramadol, morphine, acetaminophen, hydrocodone)
  • Antihistamine (cetirizine)
  • Antacid (cimetidine)
  • Blood thinner (warfarin)
  • Anti-anxiety (alprazolam)
  • Anti-hypertensive (metoprolol)

Safety Precautions and Warnings 

  1. Avoid consuming alcohol with Mirtazapine tablets as it may interact and cause increased sedative side effects. 
  1. Do not take Mirtazapine without your doctor’s consultation if you are pregnant or breastfeeding your baby. 
  1. Mirtazapine may cause increased sleepiness, dizziness, and drowsiness therefore do not take it while driving or operating machinery. 
  1. Store the Mirtazapine tablets in a cool and dry place away from direct sunlight. 
  1. Keep the Mirtazapine tablets away from children and pets. Properly dispose of expired and discarded medicines. 


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